1H, 15N and 13C assignment of the amyloidogenic protein medin using fast-pulsing NMR techniques

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1H, 15N and 13C assignment of the amyloidogenic protein medin using fast-pulsing NMR techniques.

Thirty-one proteins are known to form extracellular fibrillar amyloid in humans. Molecular information about many of these proteins in their monomeric, intermediate or fibrillar form and how they aggregate and interact to form the insoluble fibrils is sparse. This is because amyloid proteins are notoriously difficult to study in their soluble forms, due to their inherent propensity to aggregate...

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ژورنال

عنوان ژورنال: Biomolecular NMR Assignments

سال: 2015

ISSN: 1874-2718,1874-270X

DOI: 10.1007/s12104-015-9641-z